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What causes of ankylosing spondylitis?

Ankylosing Spondylitis – Causes (Short):

Genetic factor – Mainly linked with the HLA-B27.
Immune system problem – Body attacks its own joints and spine.
Family history – Higher risk if relatives have the disease.
Environmental triggers – Some infections may trigger it.
In short: It is mainly caused by genetic predisposition and abnormal immune response.

What are the symptoms ankylosing spondylitis?

Symptoms of Ankylosing Spondylitis:

Chronic lower back pain and stiffness
Morning stiffness that improves with movement
Pain in hips or buttocks
Reduced flexibility of the spine
Fatigue (tiredness)
In some cases eye inflammation (uveitis) 

How is ankylosing spondylitis diagnosed?

Diagnosis of Ankylosing Spondylitis:

Clinical examination – Checking spine movement and pain.
Imaging tests – X-ray or MRI of the sacroiliac joints and spine.
Blood test – To detect the HLA-B27.
Inflammation markers – ESR and CRP levels.

How ankylosing spondylitis is treated?

Treatment of Ankylosing Spondylitis:

Medications 💊 – Pain relievers and anti-inflammatory drugs (NSAIDs).
Physiotherapy & exercise 🧘 – To maintain spine flexibility and posture.
Biologic drugs – For severe inflammation when NSAIDs don’t work.
Surgery 🏥 – Rarely needed, only in severe joint damage.
In short: Treatment focuses on reducing pain, controlling inflammation, and maintaining mobility.
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